Interaction of Short Peptides and Free Amino Acids: a New Approach to Tissue Rejuvenation and Disease Therapy

Short peptides and amino acids play an important role in the regulation of key physiological processes in both normal and pathological conditions. They are signaling molecules that can actively interact with cellular receptors, affecting the growth and development of tissues, and also participate in the mechanisms of aging. Based on the latest scientific research, the potential of short peptides and free amino acids in tissue rejuvenation and the prevention of various diseases is considered.

Studies have shown that short peptides and free amino acids promote increased growth of cells in the cerebral cortex, heart, muscle tissue, liver, spleen and blood vessels. For example, the presence of terminal amino acids in peptides contributed to increased tissue growth, increasing the growth area index by 20-22%, and the combination of terminal amino acids of peptides and similar free amino acids increased efficiency by 31-41%. .

Short peptides exert therapeutic effects at the molecular level, targeting specific pathological processes, such as the accumulation of amyloid plaques in Alzheimer’s disease or the activation of certain cellular signals in cancer cells. This opens up new opportunities for targeted therapy, reducing side effects and improving the quality of life of patients.

Research shows that short peptides modulate the immune system, making them promising agents for the development of new vaccines, especially in oncology. Short peptides are used to activate the immune system and are used in general immunotherapy in the form of dietary supplements and biologically active supplements.

Of particular interest are the effects of the combined action of peptides and free amino acids on organotypic tissue cultures. In experiments, short peptides stimulated the growth of cerebral cortex explants by 20%, which is statistically significant compared to the control group. When culturing fragments of the cerebral cortex in the presence of the peptide and free amino acid, an 18% increase in growth was observed. Similar results were obtained for other tissues such as heart, liver and spleen.

The use of short peptides and free amino acids stimulates the rapid metabolism of these molecules in the body, which increases their effectiveness. A key area of research is the development of methods for obtaining natural short peptides with improved pharmacokinetic characteristics.

The combined use of short peptides and free amino acids provides a powerful platform for the development of nutritional supplements, safe and effective methods for the prevention of many diseases. Their ability to rejuvenate tissue and their potential to prevent serious diseases open up new opportunities for prevention and therapy.