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Peptides are the informational alphabet of life. The existence of all living organisms is made possible by the interaction of peptides and deoxyribonucleic acid (DNA) - the primary functional molecules in nature that carry hereditary information and determine all cellular functions.
Peptides regulate gene expression in all types of living organisms on Earth, including bacteria, plants, insects, amphibians, birds, rodents, and humans. Molecular docking methods have revealed that short peptides, consisting of 2-4 amino acids, are capable of binding to all spatial structures of the DNA double helix at every possible site. Their influence leads to the activation of heterochromatin in cell nuclei, the increase of telomerase activity and the elongation of telomeres in fibroblasts, the induction of differentiation in pluripotent cells, and the reduction of chromosomal aberrations.
Molecular, genetic, clinical, and experimental research unequivocally demonstrates the high activity of short peptides, their ability to affect gene expression, and enhance protein synthesis in all living organisms. Peptides contribute to the functioning of organisms up to the highest species limit. They are the primary informational molecules.
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